Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene-environment interaction involved in cholangiocarcinoma in the Thai population: polymorphisms of DNA repair genes, smoking and use of alcohol.

BMJ open - 21 Oct 2014

Songserm Nopparat, Promthet Supannee, Pientong Chamsai, Ekalaksananan Tipaya, Chopjitt Peechanika, Wiangnon Surapon

Abstract excerpt

OBJECTIVE: Cholangiocarcinoma (CCA) is the most common malignancy in a Northeast Thai population. Smoking and alcohol drinking are associated with the production of free radical intermediates, which can cause several types of DNA lesions. Reduced repair of these DNA lesions would constitute an important risk factor for cancer development. We therefore examined whether polymorphisms in DNA base-excision repair...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Drinking
Share to Bile Duct Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bile Ducts, Intrahepatic

Share to Cholangiocarcinoma

Share to DNA Glycosylases

Share to Gene-Environment Interaction

Share to Thailand

Share to X-ray Repair Cross Complementing Protein 1

Source

Open in PubMed Open full text

Identifiers

PMID: 25335960
DOI: 10.1136/bmjopen-2014-005447
PMCID: PMC4208049

Genes

OGG1
XRCC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene-environment interaction involved in cholangiocarcinoma in the Thai population: polymorphisms of DNA repair genes, smoking and use of alcohol.PMID 25335960Read ↗

Risk factors for cholangiocarcinoma in high-risk area of Thailand: role of lifestyle, diet and methylenetetrahydrofolate reductase polymorphisms.Semantic proximity Read ↗

MTHFR polymorphisms and Opisthorchis viverrini infection: a relationship with increased susceptibility to cholangiocarcinoma in Thailand.Semantic proximity Read ↗

The XRCC 1 DNA repair gene modifies the environmental risk of stomach cancer: a hospital-based matched case-control study.Semantic proximity Read ↗

Lifestyle habits and genetic susceptibility and the risk of esophageal cancer in the Thai population.Semantic proximity Read ↗

Genetic factors in the pathogenesis of cholangiocarcinoma.Semantic proximity Read ↗

Combined effects of polymorphisms of DNA-repair protein genes and metabolic enzyme genes on the risk of cholangiocarcinoma.Semantic proximity Read ↗

Polymorphisms of XRCC1 and XRCC2 DNA Repair genes and Interaction with Environmental Factors Influence the Risk of Nasopharyngeal Carcinoma in Northeast India.Semantic proximity Read ↗

XRCC1 gene polymorphism, diet and risk of colorectal cancer in Thailand.Semantic proximity Read ↗

Opisthorchiasis with proinflammatory cytokines (IL-1β and TNF-α) polymorphisms influence risk of intrahepatic cholangiocarcinoma in Thailand: a nested case-control study.Semantic proximity Read ↗

ABCB1 genetic polymorphism and risk of upper aerodigestive tract cancers among smokers, tobacco chewers and alcoholics in an Indian population.Semantic proximity Read ↗

Association of NRF2 polymorphism with cholangiocarcinoma prognosis in Thai patients.Semantic proximity Read ↗

Association of XRCC1 p. Arg194Trp gene polymorphism with the risk of hepatocellular carcinoma in HCV Egyptian population: A pilot case-control study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.