Article
Association of microsomal epoxide hydrolase exon 3 Tyr113His and exon 4 His139Arg polymorphisms with gastric cancer in India.
Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology - 1 Jul 2013
Ghoshal Ujjala, Kumar Sushil, Jaiswal Virendra, Tripathi Shweta, Mittal Balraj, Ghoshal Uday C
Abstract excerpt
BACKGROUND: Microsomal epoxide hydrolase, an important phase II xenobiotic enzyme, exhibits polymorphisms at exon 3 (Tyr113His [T/C]) and exon 4 (His139Arg [A/G]), which modulate enzyme activity; this may affect susceptibility to cancers. We studied association between these polymorphisms and gastric cancer (GC). METHODS: In a prospective study, 77 patients with GC, 50 with peptic ulcer, and 160 healthy controls...
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