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Article

Heterogeneity of epidermal growth factor receptor status and mutations of KRAS/PIK3CA in circulating tumor cells of patients with colorectal cancer.

Clinical chemistry - 1 Jan 2013

Gasch Christin, Bauernhofer Thomas, Pichler Martin, Langer-Freitag Sabine, Reeh Matthias, Seifert Adrian M, Mauermann Oliver, Izbicki Jakob R, Pantel Klaus, Riethdorf Sabine

Abstract excerpt

BACKGROUND: Molecular characterization of circulating tumor cells (CTCs) is pivotal to increasing the diagnostic specificity of CTC assays and investigating therapeutic targets and their downstream pathways on CTCs. We focused on epidermal growth factor receptor (EGFR) and genes relevant for its...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23136247
DOI: 10.1373/clinchem.2012.188557

Genes

EGFR
KRAS
BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23136247-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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