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Genetic Heterogeneity of Single Circulating Tumour Cells in Colorectal Carcinoma

20 Oct 2020

Abstract excerpt

The aim of the present study was to isolate and investigate the genetic heterogeneities in single circulating tumour cells (CTCs) from patients with colorectal carcinoma (CRC). Twenty-eight single CTCs were collected from eight patients with CRC using a negative immunomagnetic enrichment method. After validation with glyceraldehyde 3-phosphate dehydrogenase (GAPDH) gene expression in 3 colon cancer cell lines, a...

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PMID: 33092235
DOI: 10.3390/ijms21207766

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