Article
Clinico-pathological correlation of serial measurement of circulating tumor cells in 24 metastatic colorectal cancer patients receiving chemotherapy reveals interpatient heterogeneity correlated with CEA levels but independent of KRAS and BRAF mutation.
Cancer biology & therapy - 1 Jan 2015
Das Avisnata, Kunkel Miriam, Joudeh Jamal, Dicker David T, Scicchitano Angelique, Allen Joshua E, Sarwani Nabeel, Yang Zhaohai, Kaifi Jussuf, Zhu Junjia, Liao Jason, El-Deiry Wafik S
Abstract excerpt
BACKGROUND: The Veridex CellSearch is an FDA-approved technology for enumerating circulating tumor cells in blood samples of metastatic colorectal cancer mCRC) patients and has prognostic value. It is important to understand how counts of circulating tumor cells (CTCs), which are advocated to be tools for "liquid biopsy" of tumors, correlate with clinical and pathologic variables of significance in these...
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