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Article

KRAS mutation analysis of single circulating tumor cells from patients with metastatic colorectal cancer.

BMC cancer - 3 May 2017

Kondo Yuurin, Hayashi Kazuhiko, Kawakami Kazuyuki, Miwa Yukari, Hayashi Hiroshi, Yamamoto Masakazu

Abstract excerpt

BACKGROUND: The molecular profiles of tumors may inform the selection of appropriate targeted therapies. Circulating tumor cells (CTCs) reflect the real-time status of tumor genotypes. CTCs exhibit high genetic heterogeneity within a patient; accordingly, the analysis of individual CTCs, including their heterogeneity, may enable more precise treatments. We analyzed KRAS mutations in single CTCs from patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28468669
DOI: 10.1186/s12885-017-3305-6
PMCID: PMC5415811

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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