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Article

Circulating tumor cells: exploring intratumor heterogeneity of colorectal cancer.

Cancer biology & therapy - 1 May 2014

Raimondi Cristina, Nicolazzo Chiara, Gradilone Angela, Giannini Giuseppe, De Falco Elena, Chimenti Isotta, Varriale Elisa, Hauch Siegfried, Plappert Linda, Cortesi Enrico, Gazzaniga Paola

Abstract excerpt

The hypothesis of the "liquid biopsy" using circulating tumor cells (CTCs) emerged as a minimally invasive alternative to traditional tissue biopsy to determine cancer therapy. Discordance for biomarkers expression between primary tumor tissue and circulating tumor cells (CTCs) has been widely re...

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Source

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Identifiers

PMID: 24521660
DOI: 10.4161/cbt.28020
PMCID: PMC4026071

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24521660-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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