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Article

Defective meiosis in telomere-silencing mutants of Schizosaccharomyces pombe.

Nature - 23 Apr 1998

Nimmo E R, Pidoux A L, Perry P E, Allshire R C

Abstract excerpt

During meiotic prophase, chromosomes frequently adopt a bouquet-like arrangement, with their telomeres clustered close to the nuclear periphery. A dramatic example of this occurs in the fission yeast, Schizosaccharomyces pombe, where all telomeres aggregate adjacent to the spindle pole body (SPB). Nuclei then undergo rapid traverses of the cell, known as 'horsetail' movement, which is led by the SPB dragging...

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Source

Identifiers

PMID: 9572142
DOI: 10.1038/33941

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Defective meiosis in telomere-silencing mutants of Schizosaccharomyces pombe.PMID 9572142Read ↗

Fission yeast mutants affecting telomere clustering and meiosis-specific spindle pole body integrity.Semantic proximity Read ↗

The meiotic bouquet promotes homolog interactions and restricts ectopic recombination in Schizosaccharomyces pombe.Semantic proximity Read ↗

Schizosaccharomyces pombe mst2+ encodes a MYST family histone acetyltransferase that negatively regulates telomere silencing.Semantic proximity Read ↗

Identification of the functional domains of the telomere protein Rap1 in Schizosaccharomyces pombe.Semantic proximity Read ↗

The Schizosaccharomyces pombe hst4(+) gene is a SIR2 homologue with silencing and centromeric functions.Semantic proximity Read ↗

Meiosis induced by inactivation of Pat1 kinase proceeds with aberrant nuclear positioning of centromeres in the fission yeast Schizosaccharomyces pombe.Semantic proximity Read ↗

Bqt2p is essential for initiating telomere clustering upon pheromone sensing in fission yeast.Semantic proximity Read ↗

Evolution of Telomeres in Schizosaccharomyces pombe and Its Possible Relationship to the Diversification of Telomere Binding Proteins.Semantic proximity Read ↗

A novel type of silencing factor, Clr2, is necessary for transcriptional silencing at various chromosomal locations in the fission yeast Schizosaccharomyces pombe.Semantic proximity Read ↗

Schizosaccharomyces pombe histone acetyltransferase Mst1 (KAT5) is an essential protein required for damage response and chromosome segregation.Semantic proximity Read ↗

The telomere protein Taz1 is required to prevent and repair genomic DNA breaks.Semantic proximity Read ↗

A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.Semantic proximity Read ↗

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