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Article

Defective meiosis in telomere-silencing mutants of Schizosaccharomyces pombe.

Nature - 23 Apr 1998

Nimmo E R, Pidoux A L, Perry P E, Allshire R C

Abstract excerpt

During meiotic prophase, chromosomes frequently adopt a bouquet-like arrangement, with their telomeres clustered close to the nuclear periphery. A dramatic example of this occurs in the fission yeast, Schizosaccharomyces pombe, where all telomeres aggregate adjacent to the spindle pole body (SPB)...

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Source

Identifiers

PMID: 9572142
DOI: 10.1038/33941

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-9572142-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Defective meiosis in telomere-silencing mutants of Schizosaccharomyces pombe.PMID 9572142Read ↗

Fission yeast mutants affecting telomere clustering and meiosis-specific spindle pole body integrity.Semantic proximity Read ↗

The meiotic bouquet promotes homolog interactions and restricts ectopic recombination in Schizosaccharomyces pombe.Semantic proximity Read ↗

Schizosaccharomyces pombe mst2+ encodes a MYST family histone acetyltransferase that negatively regulates telomere silencing.Semantic proximity Read ↗

Identification of the functional domains of the telomere protein Rap1 in Schizosaccharomyces pombe.Semantic proximity Read ↗

The Schizosaccharomyces pombe hst4(+) gene is a SIR2 homologue with silencing and centromeric functions.Semantic proximity Read ↗

Meiosis induced by inactivation of Pat1 kinase proceeds with aberrant nuclear positioning of centromeres in the fission yeast Schizosaccharomyces pombe.Semantic proximity Read ↗

Bqt2p is essential for initiating telomere clustering upon pheromone sensing in fission yeast.Semantic proximity Read ↗

Evolution of Telomeres in Schizosaccharomyces pombe and Its Possible Relationship to the Diversification of Telomere Binding Proteins.Semantic proximity Read ↗

A novel type of silencing factor, Clr2, is necessary for transcriptional silencing at various chromosomal locations in the fission yeast Schizosaccharomyces pombe.Semantic proximity Read ↗

Schizosaccharomyces pombe histone acetyltransferase Mst1 (KAT5) is an essential protein required for damage response and chromosome segregation.Semantic proximity Read ↗

The telomere protein Taz1 is required to prevent and repair genomic DNA breaks.Semantic proximity Read ↗

A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.Semantic proximity Read ↗

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