Article

Quantitative assessment of collagen architecture from routine histopathological images shows concordance with Second Harmonic Generation microscopy

2026-04-06

Abstract excerpt

Collagen organisation within the tumour microenvironment plays a critical role in tumour progression and has emerged as an important structural biomarker in cancer. Second Harmonic Generation (SHG) microscopy enables label-free visualisation and quantitative assessment of fibrillar collagen architecture; however, its high cost, specialised instrumentation, and limited field-of-view restrict routine clinical applic...

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Literature Corpus work: dd11517d-525b-5fac-9815-976879d31b07
DOI: 10.64898/2026.03.31.26349841

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