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Article

Effects of aging and gender on the spatial organization of nuclei in single human skeletal muscle cells.

Aging cell - 1 Oct 2010

Cristea Alexander, Qaisar Rizwan, Edlund Patrick K, Lindblad Joakim, Bengtsson Ewert, Larsson Lars

Abstract excerpt

The skeletal muscle fibre is a syncitium where each myonucleus regulates the gene products in a finite volume of the cytoplasm, i.e., the myonuclear domain (MND). We analysed aging- and gender-related effects on myonuclei organization and the MND size in single muscle fibres from six young (21-31 years) and nine old men (72-96 years), and from six young (24-32 years) and nine old women (65-96 years), using a...

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Identifiers

PMID: 20633000
DOI: 10.1111/j.1474-9726.2010.00594.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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