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Article

Common genetic variation of the calcium-sensing receptor and lethal prostate cancer risk.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2013

Shui Irene M, Mucci Lorelei A, Wilson Kathryn M, Kraft Peter, Penney Kathryn L, Stampfer Meir J, Giovannucci Edward

Abstract excerpt

BACKGROUND: Bony metastases cause substantial morbidity and mortality from prostate cancer (PCa). The calcium-sensing receptor (CaSR) is expressed on prostate tumors and may participate in bone metastases development. We assessed whether (i) common genetic variation in CaSR was associated with PCa risk and (ii) these associations varied by calcium intake or plasma 25-hydroxyvitamin D [25(OH)D] levels. METHODS: We...

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PMID: 23125333
DOI: 10.1158/1055-9965.EPI-12-0670-T
PMCID: PMC3538912

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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