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Article

Vitamin D pathway gene variants and prostate cancer prognosis.

The Prostate - 15 Sept 2010

Holt Sarah K, Kwon Erika M, Koopmeiners Joseph S, Lin Daniel W, Feng Ziding, Ostrander Elaine A, Peters Ulrike, Stanford Janet L

Abstract excerpt

BACKGROUND: Observational studies linking vitamin D deficiency with increased prostate cancer (PCa) mortality and the pleiotropic anticancer effects of vitamin D in malignant prostate cell lines have initiated trials examining potential therapeutic benefits of vitamin D metabolites. There have been some successes but efforts have been hindered by risk of inducing hypercalcemia. A limited number of studies have...

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Source

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Identifiers

PMID: 20687218
DOI: 10.1002/pros.21180
PMCID: PMC2927712

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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