Article
Prostate cancer in African-American men and polymorphism in the calcium-sensing receptor.
Cancer biology & therapy - 15 Jun 2010
Schwartz Gary G, John Esther M, Rowland Glovioell, Ingles Sue A
Abstract excerpt
BACKGROUND: Prospective epidemiologic studies indicate that the risk for advanced prostate cancer is increased among men with high levels of serum calcium. Because serum calcium levels are influenced by the calcium-sensing receptor (CaSR), we examined prostate cancer in African-American men in relation to three single nucleotide polymorphisms (SNPs) in the CaSR gene, A986S, R990G and Q1011E. This is the first...
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