Article
Bld10/Cep135 stabilizes basal bodies to resist cilia-generated forces.
Molecular biology of the cell - 1 Dec 2012
Bayless Brian A, Giddings Thomas H, Winey Mark, Pearson Chad G
Abstract excerpt
Basal bodies nucleate, anchor, and organize cilia. As the anchor for motile cilia, basal bodies must be resistant to the forces directed toward the cell as a consequence of ciliary beating. The molecules and generalized mechanisms that contribute to the maintenance of basal bodies remain to be discovered. Bld10/Cep135 is a basal body outer cartwheel domain protein that has established roles in the assembly of...
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