Article
Bld10p constitutes the cartwheel-spoke tip and stabilizes the 9-fold symmetry of the centriole.
Current biology : CB - 23 Oct 2007
Hiraki Madoka, Nakazawa Yuki, Kamiya Ritsu, Hirono Masafumi
Abstract excerpt
Centrioles/basal bodies have a characteristic cylindrical structure consisting of nine triplet microtubules arranged in a rotational symmetry. How this elaborate structure is formed is a major unanswered question in cell biology [1, 2]. We previously identified a 170 kDa coiled-coil protein essential for the centriole formation in Chlamydomonas. This protein, Bld10p, is the first protein shown to localize to the...
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