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Environmental factors, seven GWAS-identified susceptibility loci, and risk of gastric cancer and its precursors in a Chinese population.

Cancer medicine - 1 Mar 2017

Cai Meng, Dai Shuyang, Chen Wanqing, Xia Changfa, Lu Lingeng, Dai Shuguang, Qi Jun, Wang Minjie, Wang Meilin, Zhou Lanping, Lei Fuhua, Zuo Tingting, Zeng Hongmei, Zhao Xiaohang

Abstract excerpt

Gene-environment interactions may increase gastric cancer (GC) risk. Seven susceptibility loci identified by genome-wide association studies (GWASs) suggest that genetic factors play a role in gastric carcinogenesis. Meanwhile, Helicobacter pylori (H. pylori) infection, smoking, and alcohol drinking are also important environmental factors for gastric cancer. However, studies to explore the role of...

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PMID: 28220687
DOI: 10.1002/cam4.1038
PMCID: PMC5345626

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PRKAA1
MUC1
PSCA
ZBTB20

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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