Article
Genetic variant in miR-17-92 cluster binding sites is associated with esophageal squamous cell carcinoma risk in Chinese population.
BMC cancer - 2 Dec 2022
Shen Yi, Shao Yi, Ruan Xiaoli, Zhu Lingyan, Zang Zhaoping, Wei Tong, Nakyeyune Rena, Wei Wenqiang, Liu Fen
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) located in microRNA (miRNA) binding sites can affect the interactions between miRNAs and target genes, which is related to cancer susceptibility and tumorigenesis. However, the association between SNPs located in miR-17-92 cluster binding sites and ESCC risk remains unclear. Therefore, we aimed to explore the relationship between polymorphisms in miR-17-92...
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