Article
Integrative analysis of prognostic factors in Chinese core binding factor leukemia.
Biochemical and biophysical research communications - 23 Nov 2012
Wang Di, Qiao Chun, Xiao Min, Geng Zhe, Shang Zhen, He Jing, Huang Mei, Yang Yang, Zhang Na, Liu Yanan, Li Jianyong, Li Chunrui, Zhou Jianfeng
Abstract excerpt
The characteristics of core binding factor (CBF) leukemia appear to differ between Chinese and Caucasian patients. In this study, we analyzed the biological and clinical characteristics of 76 Chinese CBF leukemia patients out of 425 newly diagnosed acute myeloid leukemia (AML) patients. The frequency of CBF AML was 17.9%. Patients harboring t(8;21) were predominant in CBF AML. The incidence of c-kit mutation in...
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