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Article

Prognostic impact of c-KIT mutations in core binding factor acute myeloid leukemia.

Leukemia research - 1 Oct 2011

Park Sang Hyuk, Chi Hyun-Sook, Min Sook-Kyung, Park Borae G, Jang Seongsoo, Park Chan-Jeoung

Abstract excerpt

This study sought to define the prognostic impact of c-KIT mutations in core binding factor acute myeloid leukemia (CBF AML) patients. A total of 116 patients diagnosed as CBF AML in Asan Medical Center from January 1999 to May 2010 were enrolled in this study. We applied melting curve analyses and direct sequencing methods to confirm c-KIT mutations in exon 17 (mutKIT17) and exon 8 (mutKIT8). Of the total 116...

Topics

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Bone Marrow
Chromosome Inversion
Core Binding Factors
Leukemia, Myeloid, Acute
Proto-Oncogene Proteins c-kit

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Survival Analysis

Transition Temperature

Translocation, Genetic

Source

Identifiers

PMID: 21715005
DOI: 10.1016/j.leukres.2011.06.003

Genes

KIT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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