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Article

Prospective Evaluation of KIT Mutations and Long-Term Outcomes in Pediatric Core Binding Factor Acute Myeloid Leukemia: A Single Institutional Study in China.

Pediatric hematology and oncology - 1 Mar 2026

Hou Bei, Yang Feifei, Zhang Ruidong, Qin Maoquan, Li Jun, Wang Ying, Chen Hui, Li Jing, Qi Peijing, Jia Chenguang, Zheng Huyong, Gao Chao

Abstract excerpt

The overall incidence of core binding factor acute myeloid leukemia (CBF-AML) in pediatric patients has been reported to be 19%-44.3%. However, the prognostic role of KIT mutations in pediatric CBF-AML remains controversial. This study aimed to investigate whether incorporating KIT mutation status into risk stratification improves long-term outcomes. A total of 114 pediatric CBF-AML patients treated under BCH-AML...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41452105
DOI: 10.1080/08880018.2025.2601128

Genes

KIT
RUNX1
RUNX1T1
EFS
MYH11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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Prospective Evaluation of KIT Mutations and Long-Term Outcomes in Pediatric Core Binding Factor Acute Myeloid Leukemia: A Single Institutional Study in China.PMID 41452105Read ↗

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The Prognostic Significance of c-KIT Mutations in Core Binding Factor Acute Myeloid Leukemia.Semantic proximity Read ↗

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