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Article

The Prognostic Significance of c-KIT Mutations in Core Binding Factor Acute Myeloid Leukemia.

Clinical lymphoma, myeloma & leukemia - 1 Jun 2022

Shafik Nevine F, Ibraheem Dalia, Selim Marwa Mahmoud, Allam Rasha Mahmoud, Fathalla Lamiaa A

Abstract excerpt

BACKGROUND: Many recurrent mutations are encountered in core binding factor acute myeloid leukemia (CBF-AML) which may affect the prognosis. Approximately 20 to 45% of CBF-AML patients have KIT mutations which are having poor prognosis and high incidence of relapse. There is still insufficient data to categorize the patients with c-kit mutation into which risk group and there is a debate around whether Tyrosine...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 34972661
DOI: 10.1016/j.clml.2021.11.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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