Genetic variants of 6q25 and breast cancer susceptibility: a two-stage fine mapping study in a Chinese population.

doi:10.1007/s10549-011-1527-x

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Genetic variants of 6q25 and breast cancer susceptibility: a two-stage fine mapping study in a Chinese population.

Breast cancer research and treatment - 1 Oct 2011

Han Jing, Jiang Tao, Bai Hongling, Gu Hongru, Dong Jing, Ma Hongxia, Hu Zhibin, Shen Hongbing

Abstract excerpt

A recent genome-wide association study identified a novel single nucleotide polymorphism (SNP), rs2046210, in the 6q25 region as a breast cancer susceptibility locus in Chinese and subsequently replicated in a multicenter study. Further fine-mapping of this region may help identify the potential causative SNPs of breast cancer. We employed a block-based fine mapping analysis to investigate the tagging SNPs in a...

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PMID: 21528353
DOI: 10.1007/s10549-011-1527-x

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