Article
Genetic variants on chromosome 5p12 are associated with risk of breast cancer in African American women: the Black Women's Health Study.
Breast cancer research and treatment - 1 Sept 2010
Ruiz-Narvaez Edward A, Rosenberg Lynn, Rotimi Charles N, Cupples L Adrienne, Boggs Deborah A, Adeyemo Adebowale, Cozier Yvette C, Adams-Campbell Lucile L, Palmer Julie R
Abstract excerpt
Two single nucleotide polymorphisms (SNPs), rs4415084, and rs10941679 on chromosome 5p12 were associated with risk of breast cancer in a recent genome-wide association study (GWAS) of women of European ancestry. Both SNPs are located in a large high-LD region and the causal variant(s) are still unknown. We conducted a nested case-control study in a cohort of African American women to replicate and narrow the...
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