Article
Characterizing Genetic Susceptibility to Breast Cancer in Women of African Ancestry.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jul 2017
Feng Ye, Rhie Suhn Kyong, Huo Dezheng, Ruiz-Narvaez Edward A, Haddad Stephen A, Ambrosone Christine B, John Esther M, Bernstein Leslie, Zheng Wei, Hu Jennifer J, Ziegler Regina G, Nyante Sarah, Bandera Elisa V, Ingles Sue A, Press Michael F, Deming Sandra L, Rodriguez-Gil Jorge L, Zheng Yonglan, Yao Song, Han Yoo-Jeong, Ogundiran Temidayo O, Rebbeck Timothy R, Adebamowo Clement, Ojengbede Oladosu, Falusi Adeyinka G, Hennis Anselm, Nemesure Barbara, Ambs Stefan, Blot William, Cai Qiuyin, Signorello Lisa, Nathanson Katherine L, Lunetta Kathryn L, Sucheston-Campbell Lara E, Bensen Jeannette T, Chanock Stephen J, Marchand Loic Le, Olshan Andrew F, Kolonel Laurence N, Conti David V, Coetzee Gerhard A, Stram Daniel O, Olopade Olufunmilayo I, Palmer Julie R, Haiman Christopher A
Abstract excerpt
Background: Genome-wide association studies have identified approximately 100 common genetic variants associated with breast cancer risk, the majority of which were discovered in women of European ancestry. Because of different patterns of linkage disequilibrium, many of these genetic markers may not represent signals in populations of African ancestry.Methods: We tested 74 breast cancer risk variants and...
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