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Article

N-Arachidonyl glycine does not activate G protein-coupled receptor 18 signaling via canonical pathways.

Molecular pharmacology - 1 Jan 2013

Lu Van B, Puhl Henry L, Ikeda Stephen R

Abstract excerpt

Recent studies propose that N-arachidonyl glycine (NAGly), a carboxylic analogue of anandamide, is an endogenous ligand of the Gα(i/o) protein-coupled receptor 18 (GPR18). However, a high-throughput β-arrestin-based screen failed to detect activation of GPR18 by NAGly (Yin et al., 2009; JBC, 18:1...

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Source

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Identifiers

PMID: 23104136
DOI: 10.1124/mol.112.081182
PMCID: PMC3533477

Genes

GPR18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23104136-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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