Article
Delta9-tetrahydrocannabinol and endogenous cannabinoid anandamide directly potentiate the function of glycine receptors.
Molecular pharmacology - 1 Mar 2006
Hejazi Nadia, Zhou Chunyi, Oz Murat, Sun Hui, Ye Jiang Hong, Zhang Li
Abstract excerpt
Anandamide (AEA) and delta9-tetrahydrocannabinol (THC) are endogenous and exogenous ligands, respectively, for cannabinoid receptors. Whereas most of the pharmacological actions of cannabinoids are mediated by CB1 receptors, there is also evidence that these compounds can produce effects that are not mediated by the activation of identified cannabinoid receptors. Here, we report that THC and AEA, in a CB1...
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