Regulators of G protein signaling attenuate the G protein-mediated inhibition of N-type Ca channels.

doi:10.1085/jgp.113.1.97

Back to search

Article

Regulators of G protein signaling attenuate the G protein-mediated inhibition of N-type Ca channels.

The Journal of general physiology - 1 Jan 1999

Melliti K, Meza U, Fisher R, Adams B

Abstract excerpt

Regulators of G protein signaling (RGS) proteins bind to the alpha subunits of certain heterotrimeric G proteins and greatly enhance their rate of GTP hydrolysis, thereby determining the time course of interactions among Galpha, Gbetagamma, and their effectors. Voltage-gated N-type Ca channels me...

Topics

Calcium Channels
Cell Line
Electric Stimulation
Electrophysiology
GTP-Binding Proteins
Humans
Kinetics
Membrane Potentials
Mutation
Patch-Clamp Techniques
Plasmids
Signal Transduction

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.