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Article

Genetic association analysis of complex diseases incorporating intermediate phenotype information.

PloS one - 1 Jan 2012

Li Yafang, Huang Jian, Amos Christopher I

Abstract excerpt

Genetic researchers often collect disease related quantitative traits in addition to disease status because they are interested in understanding the pathophysiology of disease processes. In genome-wide association (GWA) studies, these quantitative phenotypes may be relevant to disease development and serve as intermediate phenotypes or they could be behavioral or other risk factors that predict disease risk....

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Identifiers

PMID: 23094028
DOI: 10.1371/journal.pone.0046612
PMCID: PMC3477105

Genes

CHRNA3
CHRNA5
CHRNB4
TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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