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Article

Analysis of secondary phenotype involving the interactive effect of the secondary phenotype and genetic variants on the primary disease.

Annals of human genetics - 1 Nov 2012

Wang Jian, Shete Sanjay

Abstract excerpt

A genome-wide association (GWA) study is usually designed as a case-control study, where the presence and absence of the primary disease define the cases and controls, respectively. Using the existing data from GWA studies, investigators are also trying to identify the association between genetic variants and secondary phenotypes, which are defined as traits associated with the primary disease. However, recent...

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Identifiers

PMID: 22881407
DOI: 10.1111/j.1469-1809.2012.00725.x
PMCID: PMC3472120

Genes

NAT2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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