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Article

Genome-wide association and network analysis of lung function in the Framingham Heart Study.

Genetic epidemiology - 1 Sept 2014

Liao Shu-Yi, Lin Xihong, Christiani David C

Abstract excerpt

Single nucleotide polymorphisms have been found to be associated with pulmonary function using genome-wide association studies. However, lung function is a complex trait that is likely to be influenced by multiple gene-gene interactions besides individual genes. Our goal is to build a cellular network to explore the relationship between pulmonary function and genotypes by combining SNP level and network analyses...

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Identifiers

PMID: 25044411
DOI: 10.1002/gepi.21841
PMCID: PMC4127157

Genes

CTNNB1
EPHB1
LYN
NRG1
SMAD3
TGFBR2
VCAN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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