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Article

CD34 marks angiogenic tip cells in human vascular endothelial cell cultures.

Angiogenesis - 1 Mar 2012

Siemerink Martin J, Klaassen Ingeborg, Vogels Ilse M C, Griffioen Arjan W, Van Noorden Cornelis J F, Schlingemann Reinier O

Abstract excerpt

The functional shift of quiescent endothelial cells into tip cells that migrate and stalk cells that proliferate is a key event during sprouting angiogenesis. We previously showed that the sialomucin CD34 is expressed in a small subset of cultured endothelial cells and that these cells extend filopodia: a hallmark of tip cells in vivo. In the present study, we characterized endothelial cells expressing CD34 in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Human Umbilical Vein Endothelial Cells

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Source

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Identifiers

PMID: 22249946
DOI: 10.1007/s10456-011-9251-z
PMCID: PMC3274677

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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