Article

BMP4 inhibits corneal neovascularization by interfering with tip cells in angiogenesis

2023-04-14

Abstract excerpt

Corneal neovascularization (CNV) can lead to impaired corneal transparency, resulting in vision loss or blindness. The primary pathological mechanism underlying CNV is an imbalance between pro-angiogenic and anti-angiogenic factors, with inflammation playing a crucial role. Notably, a vascular endothelial growth factor（VEGF）-A gradient triggers the selection of single endothelial cells（ECs） into primary tip cells...

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Literature Corpus work: b413c500-a2fb-5358-8947-b3a22f61319a
DOI: 10.21203/rs.3.rs-2748603/v1

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