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Article

Mutation of Elfn1 in mice causes seizures and hyperactivity.

PloS one - 1 Jan 2013

Dolan Jackie, Mitchell Kevin J

Abstract excerpt

A growing number of proteins with extracellular leucine-rich repeats (eLRRs) have been implicated in directing neuronal connectivity. We previously identified a novel family of eLRR proteins in mammals: the Elfns are transmembrane proteins with 6 LRRs, a fibronectin type-3 domain and a long cytoplasmic tail. The recent discovery that Elfn1 protein, expressed postsynaptically, can direct the elaboration of...

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Identifiers

PMID: 24312227
DOI: 10.1371/journal.pone.0080491
PMCID: PMC3842350

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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