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Article

The ydaO motif is an ATP-sensing riboswitch in Bacillus subtilis.

Nature chemical biology - 1 Dec 2012

Watson Peter Y, Fedor Martha J

Abstract excerpt

We report what is to our knowledge the first natural RNA that regulates gene expression in response to intracellular ATP. Using a biochemical screen, we found that several putative riboswitches bind ATP in vitro. The ydaO motif specifically bound ATP and regulated expression of endogenous and reporter genes in response to ATP concentrations in Bacillus subtilis. This discovery demonstrates a role for RNAs in...

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Identifiers

PMID: 23086297
DOI: 10.1038/nchembio.1095

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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