Article
New tricks for an old dogma: riboswitches as cis-only regulatory systems.
Molecular cell - 1 Jun 2003
Stormo Gary D
Abstract excerpt
Riboswitches are mRNAs that can act as direct sensors of small molecules to control their own expression. In the May 30, 2003, issue of Cell, Mandal et al. show that cis elements in mRNAs involved in purine metabolism measure the effector molecule concentration with sensitivity and specificity, and control expression of adjacent genes. Analysis of several recently discovered riboswitches suggests that this may be...
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