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Article

Mutational analysis of the purine riboswitch aptamer domain.

Biochemistry - 20 Nov 2007

Gilbert Sunny D, Love Crystal E, Edwards Andrea L, Batey Robert T

Abstract excerpt

The purine riboswitch is one of a number of mRNA elements commonly found in the 5'-untranslated region capable of controlling expression in a cis-fashion via its ability to directly bind small-molecule metabolites. Extensive biochemical and structural analysis of the nucleobase-binding domain of the riboswitch, referred to as the aptamer domain, has revealed that the mRNA recognizes its cognate ligand using an...

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Share to 5' Untranslated Regions
Share to Aptamers, Nucleotide
Share to Bacillus subtilis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Guanine

Share to Purines

Share to Regulatory Sequences, Ribonucleic Acid

Share to RNA, Bacterial

Share to Thermodynamics

Source

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Identifiers

PMID: 17960911
DOI: 10.1021/bi700410g
PMCID: PMC2556308

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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