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Clinical significance of risk-reducing salpingo-oophorectomy in patients with BRCA1/2 mutation.

Journal of gynecology obstetrics and human reproduction - 1 Oct 2023

Abay Merve, Ozgen Levent, Yalcin Yakup, Ozerkan Kemal

Abstract excerpt

OBJECTIVE: Serous tubal intraepithelial carcinoma (STIC) is a precursor lesion which is located in the distal fallopian tube and causes high grade serous ovarian carcinoma (HGSOC). The incidence of STIC for women underwent risk reducing salpingo-oophorectomy for BRCA mutation varies from 0.6 to 7% and its clinical outcomes are still unclear. The aim of this study was to demonstrate the incidence of STIC and HGSOC...

Topics

Humans
Female
Salpingo-oophorectomy
BRCA1 Protein
Retrospective Studies
Clinical Relevance
BRCA2 Protein
Fallopian Tube Neoplasms
Cystadenocarcinoma, Serous
Peritoneal Neoplasms
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37573025
DOI: 10.1016/j.jogoh.2023.102642

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Clinical significance of risk-reducing salpingo-oophorectomy in patients with BRCA1/2 mutation.PMID 37573025Read ↗

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