Article
TACR1 genotypes predict fMRI response to alcohol cues and level of alcohol dependence.
Alcoholism, clinical and experimental research - 1 Jan 2013
Blaine Sara, Claus Eric, Harlaar Nicole, Hutchison Kent
Abstract excerpt
BACKGROUND: The tachykinin receptor 1 (TACR1) gene is a promising candidate gene in the search for the genetic basis of alcohol dependence (AD); TACR1 antagonists improve symptomology not only in preclinical models of AD but also in a clinical sample of detoxified alcoholics (George et al., Science 319:1536, 2008). The purpose of the current study was to determine whether TACR1 single nucleotide polymorphisms...
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