Article
A polymorphism in GABRA2 is associated with the medial frontal response to alcohol cues in an fMRI study.
Alcoholism, clinical and experimental research - 1 Dec 2010
Kareken David A, Liang Tiebing, Wetherill Leah, Dzemidzic Mario, Bragulat Veronique, Cox Cari, Talavage Thomas, O'Connor Sean J, Foroud Tatiana
Abstract excerpt
BACKGROUND: Significant evidence has accumulated to suggest an association between single-nucleotide polymorphisms (SNPs) in the GABRA2 gene and alcoholism. However, research has yet to show an association between these polymorphisms and the human brain's reward system function. In this study, we stratified subjects who had participated in an fMRI study of alcohol cue responses according to their genotype at a...
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