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Article

The effects of single nucleotide polymorphisms in glutamatergic neurotransmission genes on neural response to alcohol cues and craving.

Addiction biology - 1 Nov 2015

Bach Patrick, Kirsch Martina, Hoffmann Sabine, Jorde Anne, Mann Karl, Frank Josef, Charlet Katrin, Beck Anne, Heinz Andreas, Walter Henrik, Rietschel Marcella, Kiefer Falk, Vollstädt-Klein Sabine

Abstract excerpt

The aim of the current study was to determine genotype effects of four single nucleotide polymorphisms (SNPs) in the genes of the N-Methyl-d-aspartate receptor (GRIN1, GRIN2A, GRIN2C) and kainate receptor (GRIK1), which have been previously associated with alcoholism, on behavior, neural cue-reactivity and drinking outcome. Eighty-six abstinent alcohol dependent patients were recruited from an in-patient setting....

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Source

Identifiers

PMID: 26289945
DOI: 10.1111/adb.12291

Genes

GRIK1
GRIN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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