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Article

Cannabinoid receptor 1 gene is associated with alcohol dependence.

Alcoholism, clinical and experimental research - 1 Feb 2012

Marcos Miguel, Pastor Isabel, de la Calle Cristina, Barrio-Real Laura, Laso Francisco-Javier, González-Sarmiento Rogelio

Abstract excerpt

BACKGROUND: Alcohol dependence (AD) vulnerability is determined by a complex array of genetic factors. Given the potential role of endocannabinoid system in AD, polymorphisms within cannabinoid receptor 1 gene (CNR1) have been potentially associated with susceptibility to this disease. We thus aimed to examine the relationship between 3 allelic variants of CNR1 (rs6454674, rs1049353, and rs806368) and AD....

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Source

Identifiers

PMID: 22085192
DOI: 10.1111/j.1530-0277.2011.01623.x

Genes

CNR1

Provenance

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