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Article

Prevalence, clinico-pathological value, and co-occurrence of PDGFRA abnormalities in diffuse gliomas.

Neuro-oncology - 1 Nov 2012

Alentorn Agustí, Marie Yannick, Carpentier Catherine, Boisselier Blandine, Giry Marine, Labussière Marianne, Mokhtari Karima, Hoang-Xuan Khê, Sanson Marc, Delattre Jean-Yves, Idbaih Ahmed

Abstract excerpt

PDGFRA is a critical gene in glioma biology. Similar to EGFR, PDGFRA has been shown to be overexpressed, amplified, mutated, or truncated in gliomas, particularly glioblastomas. In addition, PDGFRA has been recently shown to be rearranged in glioblastoma. However, the frequency, cooccurrence, and clinical value of PDGFRA abnormalities in diffuse gliomas remain unclear. We investigated PDGFRA abnormalities and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23074200
DOI: 10.1093/neuonc/nos217
PMCID: PMC3480267

Genes

PDGFRA
EGFR
KDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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