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Amplification of the PDGFRA, KIT and KDR genes in glioblastoma: a population-based study

7 Mar 2011

Abstract excerpt

The aim of this study was to establish the frequency of amplification of tyrosine kinase receptor genes PDGFRA, KIT and KDR (VEGFR2) at 4q12 in glioblastomas at a population level, and to assess whether such alterations have any clinical impact. Screening of 390 glioblastomas from a population-based study by differential PCR revealed amplification of the PDGFRA, KIT and KDR genes in 33 (8.5%), 17 (4.4%) and 13...

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PMID: 21382095
DOI: 10.1111/j.1440-1789.2011.01204.x

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Amplification of the PDGFRA, KIT and KDR genes in glioblastoma: a population-based studyPMID 21382095Read ↗

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