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High-resolution genomic analysis suggests the absence of recurrent genomic alterations other than SMARCB1 aberrations in atypical teratoid/rhabdoid tumors.

Genes, chromosomes & cancer - 1 Feb 2013

Hasselblatt Martin, Isken Sarah, Linge Anna, Eikmeier Kristin, Jeibmann Astrid, Oyen Florian, Nagel Inga, Richter Julia, Bartelheim Kerstin, Kordes Uwe, Schneppenheim Reinhard, Frühwald Michael, Siebert Reiner, Paulus Werner

Abstract excerpt

Atypical teratoid/rhabdoid tumor (AT/RT) is a rare malignant pediatric brain tumor characterized by genetic alterations affecting the SMARCB1 (hSNF5/INI1) locus in chromosome band 22q11.2. To identify potential additional genetic alterations, high-resolution genome-wide analysis was performed using a molecular inversion probe single-nucleotide polymorphism (MIP SNP) assay (Affymetrix OncoScan formalin-fixed...

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Share to Chromosomal Proteins, Non-Histone
Share to Chromosome Aberrations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 22

Share to In Situ Hybridization, Fluorescence

Share to Loss of Heterozygosity

Share to Multiplex Polymerase Chain Reaction

Share to Rhabdoid Tumor

Share to SMARCB1 Protein

Source

Identifiers

PMID: 23074045
DOI: 10.1002/gcc.22018

Genes

SMARCB1
MIP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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