Genomic analysis using high-density single nucleotide polymorphism-based oligonucleotide arrays and multiplex ligation-dependent probe amplification provides a comprehensive analysis of INI1/SMARCB1 in malignant rhabdoid tumors.

doi:10.1158/1078-0432.CCR-08-2091

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Article

Genomic analysis using high-density single nucleotide polymorphism-based oligonucleotide arrays and multiplex ligation-dependent probe amplification provides a comprehensive analysis of INI1/SMARCB1 in malignant rhabdoid tumors.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Mar 2009

Jackson Eric M, Sievert Angela J, Gai Xiaowu, Hakonarson Hakon, Judkins Alexander R, Tooke Laura, Perin Juan Carlos, Xie Hongbo, Shaikh Tamim H, Biegel Jaclyn A

Abstract excerpt

PURPOSE: A high-resolution genomic profiling and comprehensive targeted analysis of INI1/SMARCB1 of a large series of pediatric rhabdoid tumors was done. The aim was to identify regions of copy number change and loss of heterozygosity (LOH) that might pinpoint additional loci involved in the development or progression of rhabdoid tumors and define the spectrum of genomic alterations of INI1 in this malignancy....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19276269
DOI: 10.1158/1078-0432.CCR-08-2091
PMCID: PMC2668138

Genes

SMARCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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