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Article

Genetic heterogeneity in rhabdomyosarcoma revealed by SNP array analysis.

Genes, chromosomes & cancer - 1 Jan 2016

Walther Charles, Mayrhofer Markus, Nilsson Jenny, Hofvander Jakob, Jonson Tord, Mandahl Nils, Øra Ingrid, Gisselsson David, Mertens Fredrik

Abstract excerpt

Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children and adolescents. Alveolar (ARMS) and embryonal (ERMS) histologies predominate, but rare cases are classified as spindle cell/sclerosing (SRMS). For treatment stratification, RMS is further subclassified as fusion-positive (FP-RMS) or fusion-negative (FN-RMS), depending on whether a gene fusion involving PAX3 or PAX7 is present or not. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26482321
DOI: 10.1002/gcc.22285

Genes

ASCC3
CDK4
ERBB2
MYCN
MYOD1
PAX3
PAX7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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