Article
Molecular genetics of atypical teratoid/rhabdoid tumor.
Neurosurgical focus - 15 Jan 2006
Biegel Jaclyn A
Abstract excerpt
Rhabdoid tumors are extremely aggressive malignancies that generally occur in infants and young children. The most common locations are the kidney and central nervous system (atypical teratoid/rhabdoid tumor [RT]), although RTs can also arise in most soft-tissue sites. Rhabdoid tumors in all anatomical locations have a similar molecular origin. Mutation or deletion of both copies of the hSNF5/INI1 gene that maps...
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