Article
Characteristics of core promoter and precore stop codon mutants of hepatitis B virus in Vietnam.
Journal of medical virology - 1 Oct 2004
Huy Tran Thien Tuan, Ushijima Hiroshi, Quang Vo Xuan, Ngoc Trinh Thi, Hayashi Shigeki, Sata Tetsutaro, Abe Kenji
Abstract excerpt
In Asia, genotypes B and C are the most common genotypes of hepatitis B virus (HBV); and genotype C causes more severe liver disease. Core promoter/precore (CP/PC) mutants, known to be linked to these genotypes, could have an impact on the progression and severity of liver disease. Sera of 115 patients, including 39 acute and 76 chronic Vietnamese HBV infected patients, were tested for their liver profile, HBeAg,...
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