Article
Analysis of SNP rs16754 of WT1 gene in a series of de novo acute myeloid leukemia patients.
Annals of hematology - 1 Dec 2012
Luna Irene, Such Esperanza, Cervera Jose, Barragán Eva, Jiménez-Velasco Antonio, Dolz Sandra, Ibáñez Mariam, Gómez-Seguí Inés, López-Pavía María, Llop Marta, Fuster Óscar, Oltra Silvestre, Moscardó Federico, Martínez-Cuadrón David, Senent M Leonor, Gascón Adriana, Montesinos Pau, Martín Guillermo, Bolufer Pascual, Sanz Miguel A
Abstract excerpt
The single nucleotide polymorphism (SNP) rs16754 of the WT1 gene has been previously described as a possible prognostic marker in normal karyotype acute myeloid leukemia (AML) patients. Nevertheless, the findings in this field are not always reproducible in different series. One hundred and seventy-five adult de novo AML patients were screened with two different methods for the detection of SNP rs16754:...
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