Article
Analysis of WT1 mutations, expression levels and single nucleotide polymorphism rs16754 in de novo non-M3 acute myeloid leukemia.
Leukemia & lymphoma - 1 Feb 2014
Luo Sheng, Yu Kang, Yan Qing-xian, Shen Zhi-jian, Wu Jian-b, Chen Hai-min, Gao Shen-meng
Abstract excerpt
The single nucleotide polymorphism (SNP) rs16754 of the WT1 gene has been described as a possible prognostic marker in patients with acute myeloid leukemia (AML). However, the results in this field are not reproducible in different cohorts. In this study, we investigated WT1 mutations, expression levels and SNP rs16754 in a cohort of 122 adult patients with AML. As the major allele (65.6%) in a Chinese...
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